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Event Profile

The Beneficial Effects 100-year old BCG Vaccine in Type 1 Diabetes

January 29, 2019
Emerson Hospital
133 Old Road Nine Acre Corner
Concord, MA 01742 
Not available

Guest Speaker, Denise Faustman, MD, PhD
Director of the Immunobiology Laboratory at the Massachusetts General Hospital (MGH) and an Associate Professor of Medicine at Harvard Medical Schoo

Dr. Faustman's research objective is to introduce new therapeutic concepts to treat autoimmune diseases with a focus on type 1 diabetes. These studies start with the basic science and translate through clinical trial design, manufacturing and clinical trial implementation. In the Immunobiology Lab, teams work to uncover the basic molecular and immunological mechanisms behind human and murine immune pathogenesis. Dr. Faustman is international leader as it relates to the TNF superfamily of receptors with an emphasis on the TNFR2 signaling, a pathway that is deficient in autoimmunity and a pathway used by select microorganism to restore immune balance.

As a result of participating in this activity, learners should be able to:

1. Discuss how repeat BCG vaccines can help restore immune balance in autoimmune disorders, such as type 1 diabetes, by inducing an increase in Treg suppressor T-cells and by killing cytotoxic T-cells.
2. Describe the beneficial effects of repeat BCG vaccination on glycemic control in type 1 diabetes, even in patients with advanced disease of greater than 20 years of duration, through induction of accelerated and regulated glucose uptake with aerobic glycolysis.
3. Summarize the rationale for re-introduction of the BCG vaccine for prevention of allergies and autoimmune disorders such as type 1 diabetes.

Accreditation Statement:
The Massachusetts Medical Society is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA Credit Designation Statement:
The Massachusetts Medical Society designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
To register please contact Susan Frazier, Phone: 800-944-5562, Fax: 781-464-4823
Email: by January 24, 2019

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Emerson Hospital

Sessions information is not available at this time.